Non-alcoholic fatty liver disease (NAFLD)

Non-alcoholic fatty liver disease is fat accumulation within the liver, without any history of alcohol consumption.

The liver has some amount of fat however, if the fat amount increases > 10% of liver weight it is indicative of fatty liver disease.

Risk factors

• Obesity

• Starvation

• Diabetes

• Dyslipidemia

Clinical presentation

NAFLD presents with different severity:

• Fatty liver

Deposition of fat in the liver. It is the most benign disease with minimum risk of disease progression.

• NASH (fatty liver with inflammation)

NASH presents with fat deposition along with liver inflammation

There is a greater risk for progressive liver diseases

• Cirrhosis

Cirrhosis is the most severe manifestation of NAFLD

Diagnosis

Diagnosis of NAFLD

• LFT

• FBS/serum insulin

• Lipid profile

• Thyroid profile

• USG abdomen shows hyperechoic liver and enlarged liver

• Liver biopsy if patients have a persistent elevation of liver enzymes

Treatment

• Gradual weight reduction

• Lifestyle modification

• Minimize calorie intake

• Recent treatment included ursodeoxycholic acid and Vit E

Need Expert Medical Guidance for Non-alcoholic fatty liver disease (NAFLD)?

Consult University Gold Medalist Dr. Ankita Gupta at Gastro Liver Endoscopy Centre, Greater Kailash-I, New Delhi for customized diagnostic evaluations.