E-20, Greater Kailash-1, Delhi-110048

Cirrhosis

Cirrhosis is the disease of liver characterized by hardening and fibrosis of liver. Causes of cirrhosis are

Cirrhosis is the disease of liver characterized by hardening and fibrosis of liver. Causes of cirrhosis are
  • Excessive alcohol intake
  • Hepatitis B
  • Hepatitis C
  • Non alcoholic fatty liver disease (Which occurs mostly in overweight individuals).
  • Wilson disease
  • Autoimmune hepatitis
  • Hemochromatosis.
  • Individuals with cirrhosis may be totally asymptomatic, and diagnosed on imaging on blood tests
  • Weakness and fatigue
  • Fluid in abdomen (ascites) and swelling of feet (pedal edema)
  • Vomiting of blood
  • Black stool
  • Altered behavior or unconsciousness
  • Decreased urine output

Cirrhosis is suspected in the patients with above mentioned symptoms, and is confirmed by following investigations

  • LFT
  • Ultrasonography
  • Fibroscan
  • Liver Biopsy
  • CT scan and MRI

Management of complications

  • Diet rich in calories and protein for the nutritional build up
  • Diuretics and salt restriction for fluid overload
  • Beta blockers, Endoscopy and banding for variceal bleed
  • Laxatives and L-ornithine L-Aspartate in patients with hepatic encephalopathy
  • Liver transplant may be only options in patients with advanced liver disease
  • Stopping alcohol
  • Antiviral for hepatitis B and C
  • Steroids for autoimmune Hepatitis
  • Copper chelation for wilson disease
  • Iron chelation for Hemochromatosis